Current Undergraduate Research Project: Rhenium Tripeptides
To develop a fundamental understanding of how the transition metal rhenium (Re) binds to basic tripeptide sequences for the development of Re-tripeptide radiotherapeutic drugs.
Re-tripeptides can exist in 2 diastereomeric forms that can interconvert over time. While we know thatdiastereomers can form, there is a limited understanding of how to stabilize one form preferentially over the other and there are many peptide sequences that have yet to be studied. By specifically designing the peptide sequences we can control the NxSy binding motifs and analyze how the changes we make affect the stability and diastereomer distribution of the resulting Re-tripeptide complexes.