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Welcome to Biomedical Photonics Laboratory @ Hunter

The quest for the physics of light-turbid soft matter (e.g., biological tissue and cells) interaction and the endeavor in engineering for noninvasively characterization and diagnosis of tissue and cells with light at the interface of physics, engineering and biomedical sciences are the current central themes of Biomedical Photonics Laboratory @ Hunter. With the recent advances in light sources, manipulation devices, and detectors as well as the ever-increasing computational power, biophotonics has attracted significant interest and is well positioned to tackle unmet needs and challenges in health-related imaging, monitoring and diagnosis. Biomedical Photonics Laboratory @ Hunter is devoted to address fundamental problems and make innovations in this exciting field with integrated analytical, computational, and experimental approaches.

In one part, we have developed realistic light scattering models for biological tissue and cells, and worked on improving the modeling of light interaction with biological tissue and cells - depolarization, decoherence and propagation of multiply scattered light through biological systems - to establish a solid foundation for applying light to medicine. In the other part, we study the inverse problems arisen in applying light to characterize and diagnose biological tissue and cells, and develop novel approaches for biomedical optical spectroscopy and imaging.

Our current research focuses on: (1) using light to noninvasively probe the physiological and functional change of biological systems and detect tumors at the early stage of development in both subsurface and deep tissues with engineered light; (2) development of label-free optical pathology for cancer diagnostics and prognostics with pathological specimens using quantitative microscopy and deep learning; and (3) innovations in deep tissue and brain imaging and monitoring with interferometric diffuse optical imaging.

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