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Bioinformatics Option for Chemistry Majors

Goal          Curriculum          Sequence          Advisors
Purpose and Goals

The advent of genomics and proteomics has transformed the way biomedical research is carried out. The Human Genome Projects, for example, determined the sequences of the 3 billion chemical base pairs that make up human DNA. In order to effectively extract important information from this enormous amount of data, the role of computational tools in biomedical research is rapidly increasing. In both academic and industry research, therefore, there is a strong need for scientists who is equipped with computational skills as well as with chemical and biological knowledge. The proposed modification in our biochemistry program will provide a solid step stone for our biochemistry students to dive into this exciting field of biomedical research.

The proposed, Major II, Option 3, is a modification of the existing Major II, Option 2. It is designed for our biochemistry major students interested in the burgeoning field of bioinformatics. This multi-disciplinary option will be made possible by a new teaching initiative called QuBi (Quantitative Biology), which is organized by the representatives from biology, chemistry, computer science and mathematics departments. These students will replace Biochemistry Laboratory with computational lab courses, namely, Practical Unix (CSCI 132), and Relational Database (CSCI 232).  In addition, students will be required to complete Introduction to Applied Statistics (STAT 213), Computational Molecular Biology (BIOL 425) and minimum 3 credits in the QuBi elective courses.  Among the QuBi electives, Chemical Genomics (CHEM 388) will be recommended to Option 3 students. 
 

Curriculum

Major II, Option 3 differs from the existing Major II, Option 2 in the following three aspects.  First, CHEM 378 (Biochemistry Laboratory) will be replaced with CSCI 435 and 493.66 (Database Management, and Unix Tools).  Second, Computational Molecular Biology (BIOL 425) and one semester of statistics (STAT 213) will be added as requirements.  Third, the elective requirement for Option 2, i.e., any chemistry course at the 200-level or above, will be changed to minimum 3 credits from any QuBi elective courses (CHEM 388, STAT 319, ANTHP 302 and BIOL 471).  Below is the proposed curriculum for the Major II, Option 3. 

Required

CHEM 102 General Chemistry I,        3 cr.
CHEM 104 General Chemistry II,       3 cr.
CHEM 106 General Chemistry Lab,    3 cr.
CHEM 222 Organic Chemistry I,         3 cr.
CHEM 223 Organic Chemistry Lab I,  2.5 cr
CHEM 224 Organic Chemistry II,        3 cr.
CHEM 225 Organic Chemistry Lab II , 2.5 cr.
CHEM 350 Biophysical Chemistry,       4 cr.
CHEM 376 Biochemistry I ,                  3 cr.
CHEM 377 Biochemistry II,                  3 cr.
 
BIOL 100 Principles of Biology I,         4.5 cr.
BIOL 102 Principles of Biology II,        4.5 cr.
BIOL 425 Computational Mol. Biol.,     3 cr. (NEW)
 
STAT 213 Intro. Applied Statistics,       3 cr.
 
MATH 150 Calculus I ,                          4 cr.
MATH 155 Calculus II,                          4 cr.
 
PHYS 110 or 111 General Physics I,    4.5 or 5.5 cr.
PHYS 120 or 121 General Physics II,   4.5 or 5.5 cr. 
 
CSCI 132   Practical UNIX and Programming, 3 cr.
CSCI  232  Relational Database & SQL,      3 cr.
 
Electives

CHEM 388 Chemical Genomics,           3 cr. (NEW)
BIOL 471 Special Topics (Genomics and Proteomics, Molecular Evolution, Protein Structure), 2 cr.
ANTHP 302 Human Genetics,              3 cr.
STAT 319 Bayesian Statistical Inference in the Sciences, 3 cr. (NEW)
 
TOTAL CREDITS FOR THE CHEMISTRY/BIOINFORMATICS MAJOR: 71-72 CREDITS
 

Sample Course Sequence*

*Please see advisor for individualized course plans

Fall (Year 1) – 7.5 credits

CHEM 102   (3 credits)
BIOL 100     (4.5 credits)


Spring (Year 1) – 14.5 credits

CHEM 104    (3 credits)
CHEM 106    (3 crecits)
BIOL 102     (4.5 crecits)
MATH 150    (4 crecits)

Fall (Year 2) – 9.5 credits

CHEM 222   (3 credits)   
CHEM 223   (2.5 credits)
MATH 155    (4 credits)
Spring (Year 2) – 10 credits        

CHEM 224  (3 credits)
CHEM 225  (2.5 credits)   
PHYS 110   (4.5 credits) 

Fall (Year 3) – 10.5 credits

PHYS 120     (4.5 credits)   
CSCI  132    (3 credits)
CHEM 376    (3 credits)

Spring (Year 3) – 9 credits
        

STAT 213       (3 credits)        
CHEM 377      (3 credits)
CSCI 232       (3 credits)
Fall (Year 4) – 7 credits

CHEM 350  (4 credits)   
CHEM 388  (3 credits)
Spring (Year 4) – 3 credits        

BIOL 425       (3 credits) 

Faculty Advisor

Dr Akira Kawamura, 212-772-3095, akira.kawamura@hunter.cuny.edu

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